Mediterranean Diet With Olive Oil Boosted HDL Function: PREDIMED

In an article by by  Patrice Wendling February 13, 2017 appearing at,

more evidence was presented for the beneficial effects of a mediterranian style diet:

BARCELONA, SPAIN — More research suggests that a Mediterranean-style diet supplemented with either virgin olive oil or mixed nuts enhances the function of HDL cholesterol[1].
In a subset of 296 patients at high risk of heart disease in the PREDIMED study, cholesterol efflux capacity (CEC), the first step in reverse cholesterol transport, was significantly increased at 1 year compared with baseline in those advised to eat a Mediterranean diet rich in virgin olive oil (VOO) (P=0.018) or mixed nuts (P=0.013) rather than a reduced-fat diet.
In addition, both Mediterranean-diet groups had a trend toward improved antioxidant and endothelial functions of HDL, although the changes were statistically significant only in the Mediterranean diet–VOO group.
1. Herna?ez A, Castan?er O, Elosua R, et al. Mediterranean diet improves high-density lipoprotein function in high-cardiovascular-risk individuals: A randomized controlled trial. Circulation 2017; 135:633-643.
2 of 3 20/02/2017, 2:08 PM
2. Rader DJ. Mediterranean approach to improving high-density lipoprotein function. Circulation 2017; 135:644-647. Editorial